In the univariate Cox regression analyses, predictors of AF recurrence included N-terminal prohormone of brain natriuretic peptide (NT-pro BNP), TC, and serum ALB (S3 Table), and patients with high CONUT score (HR: 6.045, 95% CI: 1.870–19.546, P =  0.003), low NRI (HR: 10.760, 95% CI: 3.843–30.129, P <  0.001), and low PNI (HR: 4.401, 95% CI: 1.958–9.892, P <  0.001) showed significantly higher AF recurrence rates (Table 4). The gene discussed is NPPB; the disease is atrial fibrillation.