OTUD4 and ovarian neoplasm: Deubiquitination is a key regulatory step in the ubiquitin‐proteasome system, where ubiquitination and deubiquitination processes regulate various cellular functions, such as protein degradation, cell cycle, and signal transduction, by adding or removing ubiquitin molecules.[44, 45] OTUD4 is an enzyme involved in the deubiquitination process and is one of the deubiquitinases (DUBs) belonging to the OTU (ovarian tumor) family.