When the transcriptional complex function of KMT2A is inhibited by mm102 in fibrotic fibroblasts, the changes in H3K4me3 modification are enriched in pathways related to aberrant transcription of oncogenes, genes associated with renal cell carcinoma, breast cancer and basal cell carcinoma (Figure 5G,H). This evidence concerns the gene KMT2A and renal cell carcinoma.