To date, ILA has been discovered that could downregulate glycolysis, NF‐κB, and HIF signaling pathways via the aryl hydrocarbon receptor,[41] and could also transcriptionally enhance function of tumor‐infiltrating CD8 T cells by changing chromatin accessibility.[29] The current study is the first demonstration representing the regulatory impact of ILA on BA metabolism, which improves the comprehension of the role of A. muciniphila and ILA. Here, NFKB1 is linked to neoplasm.