Moreover, mild COVID‐19 cases (dotted red‐line) were compared to severe (grey dots), and we observed that OPG has an AUC of 0.8 (95% CI = 0.68–1.0) with a cut‐off of 11.4 ng/mL, and a sensitivity and specificity of 81% and 72%, respectively (Figure 2C). This evidence concerns the gene TNFRSF11B and COVID-19.