RAC1 and cancer: Lamellipodia are sheet‐like protrusions that extend from the leading edge of migrating cells, driven by the polymerization of actin filaments pushing the plasma membrane forward.[13] Membrane ruffles are dynamic, wave‐like extensions of the plasma membrane that contribute to cell motility and the ability of cells to navigate through their environment.[14] Through these mechanisms, Rac1 facilitates cell migration and invasion, which are crucial for various physiological processes as well as pathological conditions such as cancer.[12]