This study analyzed a total of twenty‐eight genetic variants corresponding to the IL‐17A: rs 2275913 (68.4%), rs 3819024 (5.3%), rs 10484879 (5.3%); IL‐17F: rs 763780 (47.4%), IL‐17R: rs 879576 (11%) and IL‐23R: rs 11209026 (11%) genes in subjects with periodontitis and peri‐implantitis [42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59]. This evidence concerns the gene IL23R and periodontitis.