TBE56 degrades BACH1 in lung and breast cancer cells, and impairs breast cancer cell migration and invasion, while TBE31 has no valid effect.[492] The synthetic oleanane triterpenoid 2‐cyano‐3,12‐dioxooleana‐1,9(11)‐dien‐28‐oic acid (CDDO) serves as an activator of NRF2. The gene discussed is BACH1; the disease is breast carcinoma.