AGT and cardiac hypertrophy: The inhibition of BACH1 results in a reduction of Ang II‐ and norepinephrine‐induced CaMKII signaling pathway activation and hypertrophic gene expression in neonatal rat cardiomyocytes.[49] BACH1‐mediated enhancement of cardiac hypertrophy in response to Ang II is found to be modulated, at least partially, by AT1R expression both in vivo and in vitro.