The majority of studies showed that high BACH1 expression increases tumor angiogenesisonly one report showed that BACH1 decreases the protein levels of HO‐1, p‐AKT, p‐ERK, eNOS, HIF1A, and VEGF, and inhibits angiogenesis in pancreatic cancer cells. The gene discussed is HMOX1; the disease is familial pancreatic carcinoma.