BACH1 and coronary artery disorder: Ischemia/reperfusion (I/R) injury continues to pose a challenging issue in cases of acute ischemic heart disease subsequent to interventional therapy.[143, 144] The occurrence of oxidative stress is vital in I/R injury as it initiates a series of events that lead to tissue damage.[145] BACH1 regulates the cellular redox state and affects damage caused by oxidative stress during I/R by controlling the expression of HO‐1.