Firing activity of dystonia genes inside the globus pallidus can be clustered into three main groups: (1) genes associated with high regularity, weak bursts, and oscillations (eg, AOPEP); (2) genes associated with low regularity, strong bursts, and oscillations (eg, PLA2G6); and (3) intermediate genes (eg, VPS16). The gene discussed is AOPEP; the disease is Dystonia.