Kyoto encyclopedia of genes and genomes (KEGG) enrichment analysis indicated involvement in key pathways, including the PI3K‐Akt signaling pathway, apoptosis process, AGE‐RAGE signaling pathway, FoxO signaling pathway, fluid shear stress and atherosclerosis, p53 signaling pathway, microRNA‐related cancer pathways, Th17 cell differentiation, HIF‐1 signaling pathway, and MAPK signaling pathway (Figure 1B and Table S3, Supporting Information). The gene discussed is TP53; the disease is atherosclerosis.