NFKB1 and inflammatory bowel disease: Our finding that high AMBRA1 expression is negatively correlated with levels of NRF2 and its related antioxidative enzymes in IBD clinical samples demonstrates that upregulation of AMBRA1 promotes intestinal inflammation not only through IKK dephosphorylation and subsequent activation of NF‐κB activity but also through perturbation of physiological NRF2‐redox signaling and increased oxidative stress.