LEF1 and neoplasm: We hypothesize that these 13 genes, which exhibit low expression in 522 cells (no LEF1 expression), high expression in 544 cells (LEF1 overexpression), and decreased expression in 544 cells upon LEF1 knockdown, may influence tumor growth and transdifferentiation into SCC, as they seem to be regulated by LEF1 in our experimental system.