Moreover, our observation in the exp‐CAF system and patient specimens align with data in published datasets: through reanalysis of single‐cell RNA‐seq data from various cancers [31], we found that LEF1 exhibits greater specificity to myCAFs and iCAFs than to normal fibroblasts and that this specificity is clearer to LEF1 compared to other members of the TCF/LEF family. This evidence concerns the gene LEF1 and cancer.