Eighteen additional genes from this interactor set have been implicated in DM and as SFARI putative autism candidate genes (ANK3, CHD2, CHD3, FRMPD4, HCFC1, HDAC4, HRAS, HUWE1, PAK1, PIK3R2, RAC1, SETD1A, SLC25A1, SMAD4, TBL1X, TRIO, USP7, and USP9X), and 189 more have been implicated in DM or have a SFARI score. The gene discussed is SMAD4; the disease is autism.