Specifically, IGHG1 is also enriched in IgG4 plasma cells, indicating the potential pathogenicity of IgG4 plasma cells in IgG4 related disease.[15, 16] We calculated the number of DEGs for each B‐cell subgroup when comparing the AIP group to the normal group (defined as the post‐PBMC group or normal group, with criteria of pct >0.35 & |logFC| >0.1) (Figure 2D; Figure S2F, Supporting Information). This evidence concerns the gene IGHG1 and autoimmune pancreatitis.