To verify this result, we collected and measured the MFI of neutrophil HLA‐DR/ARG1/IL1RN/MMP9/CCL2 in peripheral blood and BALF of sepsis patients, and found that consistent with the result, the level of HLA‐DR was significantly decreased, while the levels of ARG1/IL1RN/MMP9/CCL2 were significantly increased (Figure 3D). Here, IL1RN is linked to Sepsis.