UGDH and metabolic dysfunction-associated steatohepatitis: Subsequently, UDP-glucose 6-dehydrogenase and UDP-glucuronate metabolism are found to suppress NASH pathogenesis and control hepatocyte apoptosis through inhibiting RIPK1 kinase activity, further solidifying the connection between RIPK1 kinase activity and metabolism during the pathogenesis of NASH (Zhang et al., 2023b).