An allosteric inhibitor of FGFR2 IIIb and the alternatively spliced FGFR2 IIIc, alofanib, induced apoptosis in the SKOV3 ovarian cancer cell line and reduced growth of SKOV3 xenograft tumors in association with inhibition of angiogenesis (32). The gene discussed is FGFR2; the disease is ovarian cancer.