Furthermore, many genes related to synthesizing structural proteins involved in myelination include (PMP22, MPZ), proteins of axonal transport (NEFL), genes involved in Schwann cell differentiation (EGR2), gene controlling members of signal transduction pathways (NDGR1) and genes regulating mitochondrial function (MFN2) have been identified to be responsible for the appearance and progression of CMT [14,15]. The gene discussed is MPZ; the disease is Charcot-Marie-Tooth disease.