PPS inhibited the proliferation of lung cancer A549 cells by altering the intracellular localization of human antigen R (HuR) protein (i.e., decreased cytoplasmic HuR protein expression and increased nuclei HuR protein expression), decreasing Cyclin D1 mRNA stability, and reducing Cyclin D1 protein expression. This evidence concerns the gene ELAVL1 and lung carcinoma.