OST: optical spectral transmission; HTN: hypertension; BMI: body mass index; RF: rheumatoid factor; anti-CCP: anticyclic citrullinated peptide antibodies; VAS: visual analog scale; DAS28-ESR: 28-joint count Disease Activity Score based on erythrocyte sedimentation rate; DAS28-CRP: 28-joint count Disease Activity Score based on C-reactive protein; NSAID: non-steroidal anti-inflammatory drug; csDMARD: conventional synthetic disease-modifying antirheumatic drugs; bDMARD: biologic DMARD; JAK: Janus kinase. Here, CRP is linked to hypertensive disorder.