Known founder mutations [6, 8, 9, 14, 22, 24, 27–29] were identified in tumor profiling reports of seven unique cases (8.4%; 7/83), including CHEK2 (I157T, n = 1), HOXB13 (G84E, n = 2) and MUTYH (G368D, n = 2 and Y151C, n = 2) (Supplementary Material 1 - Tables 6 and 7). The gene discussed is CHEK2; the disease is neoplasm.