Additionally, we demonstrated a marginal expression correlation between circUCK2(2,3) and UCK2 in our two independent HCC cohorts (Fig. S1L and M), and observed unchanged endogenous UCK2 expression levels upon knockdown, knockout, or overexpression of circUCK2(2,3) (Fig. S2D and E). The gene discussed is UCK2; the disease is hepatocellular carcinoma.