Recapitulation of miR-149-5p overexpression by introducing miR-149-5p mimics significantly suppressed the expression CNIH4 and SMAGP (Fig. S9D), whereas suppressing the function of miR-149-5p by introducing miR-149-5p inhibitors significantly induced the expression of CNIH4 and SMAGP (Fig. S9E), suggesting that miR-149-5p may target CNIH4 and SMAGP in HCC cells. The gene discussed is CNIH4; the disease is hepatocellular carcinoma.