CD4 and neoplasm: An early reduction of Bcl-6 along with the decrease in Bcl-6+CD4+ T cells prior to tumor implantation extended survival in Bcl6fl/flCD4CreER mice compared to control Bcl6fl/fl mice treated with M002, albeit no statistical significance.  Additionally, no significant change was noted in the median survival of saline-treated control Bcl6fl/fl mice when compared to saline-treated Bcl6fl/flCD4CreER mice (Fig. 4g and Supplementary Fig. 7f, g).