CD4 and glioblastoma: Notably, the IL-6-related signaling pathways along with MHCII-associated pathways were also highly enriched and upregulated in GBM patients post-G207 therapy and positively correlated with survival (Supplementary Fig. 10g and Supplementary Data 4), while the proportion of CD4+ T-cell memory population was significantly correlated with longer survival, as revealed via CIBERSORT analysis of our G207 clinical trial RNA-seq dataset (Fig. 6i and Supplementary Data 5).