In agreement with our interactome, regulation of ELN, COL5A2, FSTL1 and COL1A1 was demonstrated experimentally using a miR-29b mimic and antagomir in primary human skin fibroblasts and other models in the context of treatment of keloid formation and fibroplasia using miR-29b mimic Remlarsen [97]. The gene discussed is FSTL1; the disease is keloid.