Similar to our study, an association between reduced survival and low FOXP3 TIL count has been demonstrated for vulvar melanoma, head and neck, colorectal, and esophageal cancers, follicular lymphoma, diffuse large B-cell lymphoma, and Hodgkin lymphoma [35–37], although the underlying mechanism is yet to be understood. This evidence concerns the gene FOXP3 and Hodgkins lymphoma.