PD-L1 tumour cell expression in lymph node metastases showed a significant positive correlation with CD8 and PD-L1 TIL counts (Spearman correlation coefficient 0.38 and 0.32, respectively, p < 0.05 for both) (Table 3), and a significant negative correlation with tumour necrosis and tumour diameter (Spearman correlation coefficient -0.33 and -0.31, respectively, p < 0.05 for both) (Table 4). The gene discussed is CD274; the disease is neoplasm.