Also, CD3 TIL counts showed no correlations with survival in lymph node (S3 Fig) or skin metastases (p = 0.55 and 0.65; log-rank test) There was no prognostic correlation for CD8/FOXP3 ratio in skin or lymph node metastases (p = 0.28 and 0.46; log rank test). Here, FOXP3 is linked to metastatic malignant neoplasm in the lymph nodes.