To further test whether HOXBLINC is generally required for mediating the NUP98 fusion oncoprotein–driven HOX/homeotic oncogene transcription and leukemogenesis, we measured HOXBLINC lncRNA expression levels in patients with AML carrying a NUP98-HOXA9 translocation (patients 1265 and 1292) and compared with levels in the HOXBLINC-expressing OCI-AML3 cell line (Supplemental Figure 8A). This evidence concerns the gene RUNX2 and acute myeloid leukemia.