ATG5 and pachyonychia congenita: Dox induces autophagy in PC cells and downregulates miR-137 expression. Overexpression of miR-137 enhances Dox-induced apoptosis and inhibits autophagy. ATG5 is confirmed as a direct target of miR-137, and overexpression of ATG5 can reverse the antitumor effects mediated by miR-137