Remarkably enriched immune- and human disease-related pathways primarily included Coronavirus disease-COVID-19, Complement and coagulation cascades, Staphylococcus aureus infection, NF-kappa B (NF-κB) signaling pathway, B cell receptor signaling pathway, Natural killer cell mediated cytotoxicity, Fc epsilon RI signaling pathway, Inflammatory mediator regulation of TRP channels, MAPK (mitogen-activated protein kinase) signaling pathway, and Intestinal immune network for IgA production (Figure 4A; Supplementary Table S3). The gene discussed is NFKB1; the disease is COVID-19.