Several other reports have shown an elevated CXCL10 signature during COVID-19, including in BALF (39, 40, 46) and CXCL10 is a good circulating marker of disease severity (43, 47), consistent with the fact that a Th-1 signature can develop over time during severe COVID-19 (43, 48). The gene discussed is CXCL10; the disease is COVID-19.