1. Tau treatment reduced neurological deficit score in rats2. Tau treatment reduced the volume of cerebral infarction in rats3. Tau pretreatment reduced brain water content in rats4. Tau (600 mg/kg ig) treatment reduces mean blood pressure and heart rate in conscious and anesthetized rats5. Tau treatment can significantly restore the number of neurons in hippocampus and cortex after MCAO6. Tau inhibits the expression of caspase-3 in cerebral infarction area. Here, MAPT is linked to brain infarction.