BCL2 and ischemia: Additionally, Annao tablet has the potential to enhance the transcription level of Bcl-2 mRNA, augment the ratio of Bcl-2/Bax to impede apoptosis, diminish the count and protein expression of caspase-3 positive cells, decrease the number of neuronal apoptosis at the periphery of cerebral infarction, ameliorate the neurological deficit following ischemia, and elevate the count of positive neurons (Zhang Y. et al., 2020).