SIRT1 and eye disorder: Studies have demonstrated that the upregulation of SIRT1 exerts a protective effect against various eye diseases (Zhou et al., 2018; Shindler et al., 2007), and resveratrol can offer retinal neuroprotection in acute glaucoma models through the activation of SIRT1 (Chen et al., 2013; Luo et al., 2020; Luna et al., 2009).