64% of group GS participants appeared not to be the carriers of rare alleles of the studied variants of oligogenic hepatic diseases — rs1799945 (H63D), rs1800562 (C282Y), rs1800730 (S65C) of HFE gene, ΔF508 of CFTR gene, rs28929474 (PIZ), rs17580 (PIS) of SERPINA1 gene. Here, CFTR is linked to liver disorder.