To summarize, the subcutaneous administration of 200 U of insulin on days 1 and 7 postpartum does not decrease GLU, while can significantly reduce postpartum BHBA and NEFA in obese cows, as well as mitigate the loss of BCS during the peripartum period, which are crucial for the prevention and treatment of metabolic disorders. The gene discussed is INS; the disease is Other metabolic disease.