Similar results were reported by another RCT in polycystic ovary syndrome patients; even low dose of MK-7 (90 μg daily for 8 weeks) significantly reduced serum fasting insulin, homeostatic model assessment for insulin resistance and β-cell function index, increased insulin sensitivity check index, improved lipid profile parameters and decreased waist circumference and body fat mass (Tarkesh et al., 2020). Here, INS is linked to polycystic ovary syndrome.