Dividing these cells into KG+ and KR+ subsets revealed that the increased proportion of GZB+CX3CR1+ cells was most evident within the KR+ population, consistent with reinvigoration of CD8+ T cells present within the tumor at the time of photolabeling (KR+: 34.2% ± 3.5% vs. 18.9% ± 3.7%; P = 0.02; Fig. 5A and B). This evidence concerns the gene CX3CR1 and neoplasm.