A large majority of articles present verbal episodic memory measured by different tests (Free and Cued Selective Reminding Test, California Verbal Learning Test, Rey Auditory Verbal Learning Test) as the earliest measure with the best sensitivity and specificity ratio for the detection of the preclinical stage of AD and the most recent works propose to support this measure with different neuroimaging formats, genetic profiling (apolipoprotein E), or markers (Aβ, tau, p-tau) in cerebrospinal fluid [11, 12, 46, 49, 50, 53, 60-62, undefined, undefined]. Here, APOE is linked to Alzheimer disease.