IFNG and invasive breast carcinoma: Immune subtypes were classified into six types, including C1 (wound healing), C2 (IFN-gamma dominant), C3 (inflammatory), C4 (lymphocyte depleted), C5 (immunologically quiet), and C6 (TGF-gamma dominant).24,25Figure 2a illustrated that MARCH8 expression was related to different immune subtypes in most cancers like breast invasive carcinoma (BRCA) and brain lower grade glioma (LGG).