However, it was shown that tail vein-injected prominosomes derived from isolated prominin-1+ renal progenitors did not contribute to kidney repair in a mouse model after ischemia-induced acute kidney injury, whereas isolated prominin-1+ cells themselves or EVs derived from glomerulus-associated mesenchymal stromal cells could, with the latter mimicking the effect of their cell of origin [534]. Here, PROM1 is linked to acute kidney injury.