PROM1 and cancer: In most of these publications prominin-1 is used as an antigenic marker for the identification, isolation and characterization of cells with stem cell characteristics from various tissues and organs (e.g., brain, kidney, prostate, intestine) of healthy individuals [58, 59, 64–71], or as a potential prognostic biomarker for cancer patients as well as a molecular target for the eradication of cancer stem cells (reviewed in Refs [72–74]).