Aberrant SLC25A1 activity or expression has been implicated in various diseases, particularly cancer, where it supports cancer cell growth and resistance to energy stress-induced apoptosis by enhancing lipogenesis and upregulating oxidative phosphorylation (OXPHOS) (Fernandez et al, 2018; Mosaoa et al, 2021; Yang et al, 2021). The gene discussed is SLC25A1; the disease is cancer.