SLC25A1 and cancer: Further experiments using different cell death inhibitors on RSL3-treated parental and SLC25A1-depleted A375 and A549 cells revealed that only Fer-1 substantially prevented RSL3-induced cell death stimulated by SLC25A1 depletion, highlighting the significant impact of SLC25A1 on cancer cell sensitivity to ferroptosis (Fig. 1M; Appendix Fig. S1S).