ACLY and cancer: SLC25A1 and ACLY support rapid cell proliferation and epithelial-mesenchymal transition and maintain cancer stem cell stemness by upregulating fatty acid synthesis and histone acetylation (Carrer et al, 2019; Hanai et al, 2013; Lee et al, 2018; Mosaoa et al, 2021; Wen et al, 2019).