HHEX, LYL1, and GATA2 were in the Lmo2-driven ETP-ALL transcriptome and significantly enriched in the ETP-ALL subtype (Fig. 2A and Table S4) in our studies and in multiple other transcriptomic analyses of human T-ALL (14, 25, 26, 27, 29). Here, LYL1 is linked to acute lymphoblastic leukemia.