Similar to the molecular subtypes of endometrial endometrioid carcinoma defined by The Cancer Genome Atlas [24], four molecular subtypes of ovarian endometrioid carcinoma have been proposed: POLE mutant, mismatch repair (MMR) deficient, p53 abnormal, and no specific molecular profile (NSMP) [25]. The gene discussed is POLE; the disease is endometrial endometrioid carcinoma.