TTR and amyloidosis: Sixty individuals (27 males, 45%) were heterozygous carriers of one of the five TTR variants but did not fulfill the diagnostic criteria for ATTRv amyloidosis: Ser77Tyr (n = 45), Val122Ile (n = 8), The60Ala (n = 2), Val30Met (n = 4), or Val32Ala (n = 1).