Among all the participants, univariate analysis revealed a significant association between amyloid PET positivity and age (odds ratio [OR] = 1.047, 95% confidence interval [CI] = 1.012–1.083), p‐tau217 (OR = 1.241, 95% CI = 1.172–1.313), p‐tau181 (OR = 1.155, 95% CI = 1.108–1.203), GFAP (OR = 1.163, 95% CI = 1.111–1.126), cognitive stage, hyperlipidemia (OR = 0.354, 95% CI = 0.170–0.738), APOE ε4 carriers (OR = 6.452, 95% CI = 3.524–11.752), and MMSE score (OR = 0.799, 95% CI = 0.750–0.851; Table 2). Here, APOE is linked to hyperlipidemia.