Other potential contributory genes that were prioritized using the H3K9me2-neural annotation included two associated with brain and/or heart development: GRID2,62 which is known to cause an autosomal dominant cerebellar ataxia,63 and ROBO1, which is known to be important for both axonal guidance as well as cardiac differentiation.64 This evidence concerns the gene ROBO1 and autosomal dominant cerebellar ataxia.