The expression of peroxisome proliferator–activated receptor‐γ (Ppar‐gama/PPARg) and fatty acid binding protein 4 (FABP4), 2 key markers of adipocyte differentiation, including other adipogenic differentiation markers (IGFBP2, MGST3, LPL, and FASN) in BM‐MSCs from LBP + FR patients, were higher than the BM‐MSCs from LBP patients (Figure 5C). The gene discussed is IGFBP2; the disease is Low back pain.