Unlike these previous studies, the current study, due to its shorter duration, did not assess patient survival, focusing instead on the diagnostic utility of the preoperative CRP/Alb ratio in predicting disease severity. The current study's significant association of high CRP/Alb ratio with higher stage, metastasis, ascites, tumor grade, and lymph node involvement contrasts with the Fang et al. meta-analysis. The gene discussed is CRP; the disease is neoplasm.