Geng et al. demonstrated that exosomal circWDR62 acts as a miR-370-3p sponger to control O-6-Methylguanine-DNA Methyltransferase (MGMT), which is a DNA repair enzyme implicated in chemoresistance and ultimately enhances resistance to TMZ and promotes glioma progression in vitro and in vivo (30). This evidence concerns the gene MGMT and glioma.