Zhang et al. (2020) investigated that Echinacea polysaccharide (EP) from the Root of Echinacea purpurea  (L.)Moench. [Asteraceae] alleviated LPS-induced lung injury by inhibiting MyD88 expression and downregulating the TLR4/NF-κB signaling pathway. Zhang T. et al. (2015) discovered that timosaponin B-II (TB) from the Rhizome of Anemarrhena asphodeloides Bunge. [Asparagaceae], a major bioactive component in anemarrhena asphodeloides, inhibited MyD88 expression in LPS-induced ALI mice. This evidence concerns the gene MYD88 and acute respiratory distress syndrome.