Next, we detected numerous lymphocyte development and function associated pathways that are significantly associated with ZNF683 (HOBIT), STAT2, and IRF3 expression (Figure 5D, Supplementary Figures S9D, E), indicating that these TFs may regulate the priming, and their downstream functionalities of tumour-infiltrating NK and CD8+ T cells. Here, STAT2 is linked to neoplasm.