TLR2 and ovarian cancer: 1-steaoryl-2-15-HpETE-sn-glycero-3-phosphatidylethanolamine (SAPE-OOH), the oxidized lipid product released by ferroptotic cells, could interact with macrophages toll-like receptor 2 (TLR2), promoting M1 activation in ovarian cancer (Luo X et al., 2021).